RT Journal Article
T1 Accompanying Symptoms Overlap during Attacks in Menière's Disease and Vestibular Migraine.
A1 Lopez-Escamez, Jose Antonio
A1 Dlugaiczyk, Julia
A1 Jacobs, Julien
A1 Lempert, Thomas
A1 Teggi, Roberto
A1 von Brevern, Michael
A1 Bisdorff, Alexandre
K1 Vertigo
K1 Migraine
K1 Sensorineural hearing loss
K1 Clinical diagnosis
K1 Vestibular disorders
K1 Headache
K1 Migraña con aura
K1 Pérdida auditiva sensorineural
K1 Diagnóstico clínico
K1 Enfermedades vestibulares
K1 Cefalea
K1 Enfermedad de Meniere
AB Menière's disease and vestibular migraine (VM) are the most common causes of spontaneous recurrent vertigo. The current diagnostic criteria for the two disorders are mainly based on patients' symptoms, and no biological marker is available. When applying these criteria, an overlap of the two disorders is occasionally observed in clinical practice. Therefore, the present prospective multicenter study aimed to identify accompanying symptoms that may help to differentiate between MD, VM, and probable vestibular migraine (pVM). Two hundred and sixty-eight patients were included in the study (MD: n = 119, VM: n = 84, pVM: n = 65). Patients with MD suffered mainly from accompanying auditory symptoms (tinnitus, fullness of ear, and hearing loss), while accompanying migraine symptoms (migraine-type headache, photo-/phonophobia, visual aura), anxiety, and palpitations were more common during attacks of VM. However, it has to be noted that a subset of MD patients also experienced (migraine-type) headache during the attacks. On the other hand, some VM/pVM patients reported accompanying auditory symptoms. The female/male ratio was statistically higher in VM/pVM as compared to MD, while the age of onset was significantly lower in the former two. The frequency of migraine-type headache was significantly higher in VM as compared to both pVM and MD. Accompanying headache of any type was observed in declining order in VM, pVM, and MD. In conclusion, the present study confirms a considerable overlap of symptoms in MD, VM, and pVM. In particular, we could not identify any highly specific symptom for one of the three entities. It is rather the combination of symptoms that should guide diagnostic reasoning. The identification of common symptom patterns in VM and MD may help to refine future diagnostic criteria for the two disorders.
YR 2014
FD 2014-12-15
LK http://hdl.handle.net/10668/2282
UL http://hdl.handle.net/10668/2282
LA en
NO Lopez-Escamez JA, Dlugaiczyk J, Jacobs J, Lempert T, Teggi R, von Brevern M, et al. Accompanying Symptoms Overlap during Attacks in Menière's Disease and Vestibular Migraine. Front Neurol. 2014; 5:265
NO Journal Article;
DS RISalud
RD Apr 6, 2025