TY - JOUR AU - Ferreira, Elenilze F B AU - Silva, Luciane B AU - Costa, Glauber V AU - Costa, Josivan S AU - Fujishima, Mayara A T AU - Leão, Rozires P AU - Ferreira, Andre L S AU - Federico, Leonardo B AU - Silva, Carlos H T P AU - Rosa, Joaquin M C AU - Macedo, Williams J C AU - Santos, Cleydson B R PY - 2019 DO - 10.3390/molecules24162943 UR - http://hdl.handle.net/10668/14397 T2 - Molecules (Basel, Switzerland) AB - Leukemias are neoplasms that affect hematopoietic cells, which are developed by genetic alterations (mutations) that lead to the loss of proliferation control mechanisms (maturation and/or cell death). The α4β1 integrin receptor is a therapeutic... LA - en PB - MDPI AG KW - HCA KW - PCA KW - leukemia KW - pharmacophore KW - α4β1 receptor KW - Antineoplastic Agents KW - Cluster Analysis KW - Computer Simulation KW - Drug Screening Assays, Antitumor KW - Humans KW - Models, Molecular KW - Molecular Conformation KW - Molecular Structure KW - Peptides KW - Structure-Activity Relationship TI - Identification of New Inhibitors with Potential Antitumor Activity from Polypeptide Structures via Hierarchical Virtual Screening. TY - research article VL - 24 ER -