TY  - JOUR
AU  - Santisteban-Espejo, Antonio
AU  - Bernal-Florindo, Irene
AU  - Perez-Requena, Jose
AU  - Atienza-Cuevas, Lidia
AU  - Maira-Gonzalez, Nieves
AU  - Garcia-Rojo, Marcial
PY  - 2022
DO  - 10.3389/fonc.2022.1000762
SN  - 2234-943X
UR  - http://hdl.handle.net/10668/20685
T2  - Frontiers in oncology
AB  - Classic Hodgkin lymphoma (cHL) constitutes the most frequent lymphoma in young adults. Its histopathology is unique as a scattered tumor population, termed Hodgkin Reed-Sternberg (HRS) cells is diluted in a prominent tumor microenvironment (TME)...
LA  - en
PB  - Frontiers Research Foundation
KW  - Hodgkin reed-sternberg
KW  - Classic Hodgkin lymphoma
KW  - Digital image analysis
KW  - Tumor microenvironment
KW  - Whole-slide imaging
KW  - Área de Gestión Sanitaria de Jerez, Costa Noroeste y Sierra de Cádiz
KW  - Hodgkin disease
KW  - T-lymphocytes
KW  - Reed-Sternberg cells
KW  - Treatment outcome
TI  - Whole-slide image analysis identifies a high content of Hodgkin Reed-Sternberg cells and a low content of T lymphocytes in tumor microenvironment as predictors of adverse outcome in patients with classic Hodgkin lymphoma treated with ABVD.
TY  - research article
VL  - 12
ER  -