RT Journal Article T1 Psychosocial and sexual well-being in breast cancer survivors undergoing immediate breast reconstruction: The mediating role of breast satisfaction. A1 Gil-Olarte, Paloma A1 Gil-Olarte, M Angeles A1 Gomez-Molinero, Rocio A1 Guil, Rocio K1 Breast cancer K1 Immediate breast reconstruction K1 Mediation analysis K1 Psychosocial well-being K1 Quality of life K1 Sexual well-being AB This study aimed to explore (1) the levels of quality of life (psychosocial, physical and sexual well-being) and breast satisfaction in breast cancer patients (BCP) after immediate reconstruction (IR), considering surgery reason and surgical technique, and (2) the explanatory and predictive capacity of psychosocial well-being on breast satisfaction, and of both on sexual well-being. This prospective study included 36 BCP who underwent IR between June 2006 and December 2014. Highest levels of quality of life were found in psychosocial well-being and sexual well-being, with no statistically significant differences by surgery reason or surgical technique in any quality of life indicator or breast satisfaction. Psychosocial, physical well-being and breast satisfaction explained 56.16% of the variance in sexual well-being, where 44.67% was attributed to psychosocial well-being. In addition, breast satisfaction statistically significantly mediated the relationship between psychosocial and sexual well-being, independently of physical well-being. Our findings highlight the importance of IR in reducing psychological morbidity and preserving the quality of life and breast satisfaction. Furthermore, this research indicated that psychosocial well-being should be considered a useful personal resource for improving the sexual well-being of BCP undergoing IR both through its direct effect and the mediated effect of breast satisfaction. PB Wiley YR 2022 FD 2022-08-02 LK http://hdl.handle.net/10668/19944 UL http://hdl.handle.net/10668/19944 LA en NO Gil-Olarte P, Gil-Olarte MA, Gómez-Molinero R, Guil R. Psychosocial and sexual well-being in breast cancer survivors undergoing immediate breast reconstruction: The mediating role of breast satisfaction. Eur J Cancer Care (Engl). 2022 Nov;31(6):e13686 DS RISalud RD Apr 14, 2025