TY  - JOUR
AU  - Cohn, Allen Lee
AU  - Yoshino, Takayuki
AU  - Heinemann, Volker
AU  - Obermannova, Radka
AU  - Bodoky, György
AU  - Prausová, Jana
AU  - Garcia-Carbonero, Rocio
AU  - Ciuleanu, Tudor
AU  - Garcia-Alfonso, Pilar
AU  - Portnoy, David C
AU  - Van Cutsem, Eric
AU  - Yamazaki, Kentaro
AU  - Clingan, Philip R
AU  - Polikoff, Jonathon
AU  - Lonardi, Sara
AU  - O'Brien, Lisa M
AU  - Gao, Ling
AU  - Yang, Ling
AU  - Ferry, David
AU  - Nasroulah, Federico
AU  - Tabernero, Josep
PY  - 2017
DO  - 10.1007/s00280-017-3380-z
UR  - http://hdl.handle.net/10668/11442
T2  - Cancer chemotherapy and pharmacology
AB  - To characterize ramucirumab exposure-response relationships for efficacy and safety in patients with metastatic colorectal cancer (mCRC) using data from the RAISE study. Sparse pharmacokinetic samples were collected; a population pharmacokinetic...
LA  - en
KW  - Colorectal cancer
KW  - Exposure–response
KW  - FOLFIRI
KW  - Ramucirumab
KW  - Second line
KW  - Aged
KW  - Antibodies, Monoclonal
KW  - Antibodies, Monoclonal, Humanized
KW  - Antineoplastic Agents
KW  - Colorectal Neoplasms
KW  - Disease-Free Survival
KW  - Female
KW  - Humans
KW  - Male
TI  - Exposure-response relationship of ramucirumab in patients with advanced second-line colorectal cancer: exploratory analysis of the RAISE trial.
TY  - research article
VL  - 80
ER  -