RT Generic
T1 Evidence Update on the Relationship between Diet and the Most Common Cancers from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: A Systematic Review
A1 Ubago-Guisado, Esther
A1 Rodriguez-Barranco, Miguel
A1 Ching-Lopez, Ana
A1 Petrova, Dafina
A1 Molina-Montes, Esther
A1 Amiano, Pilar
A1 Barricarte-Gurrea, Aurelio
A1 Chirlaque, Maria-Dolores
A1 Agudo, Antonio
A1 Sanchez, Maria-Jose
K1 colorectal cancer
K1 breast cancer
K1 lung cancer
K1 prostate cancer
K1 intake
K1 alcohol
K1 fruits
K1 vegetables
K1 meat
K1 fish
K1 Defined breast-cancer
K1 Vitamin-k intake
K1 Prostate-cancer
K1 Colorectal-cancer
K1 Lung-cancer
K1 Alcohol intake
K1 Fatty-acids
K1 Heidelberg cohort
K1 Fiber intake
K1 Life-style
AB The European Prospective Investigation into Cancer and Nutrition (EPIC) is a multicentre prospective study conducted in 23 centres in 10 European countries. Here we review the findings from EPIC on the relationship between diet-related exposures and incidence or mortality from the four most frequent cancers in the European population: colorectal, breast, lung, and prostate cancer. We conducted a systematic review following PRISMA guidelines and identified 110 high-quality studies based on the EPIC cohort. Fruit and vegetable consumption had a protective effect against colorectal, breast, and lung cancer, whereas only fruit had a protective effect against prostate cancer. A higher consumption of fish and lower consumption of red and processed meat were related with a lower risk of colorectal cancer; and higher consumption of fatty fish with lower risk of breast cancer. Calcium and yogurt intake were found to protect against colorectal and prostate cancer. Alcohol consumption increased the risk for colorectal and breast cancer. Finally, adherence to the Mediterranean diet emerged as a protective factor for colorectal and breast cancer. The EPIC study results are in agreement with the latest evidence from leading authorities on cancer prevention and help to inform public prevention policies and strategies.
PB Mdpi
YR 2021
FD 2021-10-01
LK https://hdl.handle.net/10668/24685
UL https://hdl.handle.net/10668/24685
LA en
DS RISalud
RD Apr 10, 2025