RT Journal Article T1 Intra- and Interobserver Reliability of Superb Microvascular Imaging (SMI) Doppler for Assessing Placental Microvasculature A1 Garcia-Jimenez, Rocio A1 Antonio Garcia-Mejido, Jose A1 Valero, Irene A1 Fernandez-Palacin, Ana A1 Borrero, Carlota A1 Antonio Sainz-Bueno, Jose K1 superb microvascular imaging K1 SMI Doppler K1 placental microvasculature K1 reproducibility K1 reliability K1 Vascularization K1 Growth K1 Angiography AB Objective: Superb Microvascular Imaging (SMI) Doppler is a novel technique. We aim to evaluate intra- and interobserver reliability of SMI Doppler for the assessment of normal placental microvasculature. Materials and Methods: A prospective observational study was conducted including 11 pregnant patients. Ultrasonography placental assessment was performed on 28-weeks pregnant patients, by two expert examiners using SMI Doppler in one single visit. To evaluate interobserver reliability, the first examiner took measurements using SMI Doppler, followed then by the second examiner. Afterwards, the first examiner performed a second evaluation, in order to assess intraobserver reliability. Intraclass correlation coefficients (ICC) and Cohen's Kappa coefficient, and their 95% confidence intervals, were estimated for quantitative and qualitative parameters, respectively. Results: Intraobserver reliability was found to be excellent for all quantitative parameters, with all ICC values above 0.97. For qualitative variables, excellent reliability was obtained for the number of secondary villi, while the number of tertiary villi had an adequate reliability with a Cohen's Kappa coefficient of 0.792 (95% CI 0.38-1.17; p = 0.007). Interobserver ICCs ranged from 0.92 to 1.00 for all quantitative parameters, thus finding excellent interobserver reliability for all of them. An excellent reliability was also obtained for the number of secondary villi, while the reliability for the number of tertiary villi was found to be adequate. Conclusions: Our findings show that placental microvasculature measurements obtained by a single or two different examiners are reliable and reproducible. The good intra- and interobserver reliability results of SMI Doppler showed in our study stress the value of this technique in the evaluation of placental microvasculature, and thus research in this field is the step forward for the assessment of placental insufficiency. PB Imr press SN 0390-6663 YR 2022 FD 2022-08-01 LK http://hdl.handle.net/10668/21807 UL http://hdl.handle.net/10668/21807 LA en DS RISalud RD Apr 11, 2025