RT Journal Article
T1 Reply to "CMV merits further evolutionary and biological view".
A1 Gutierrez-Gutierrez, Belen
A1 Perez-Nadales, Elena
A1 Rodriguez-Baño, Jesus
A1 Torre-Cisneros, Julian
K1 Antibiotic drug resistance
K1 Clinical research/practice
K1 Infection and infectious agents-bacterial
K1 Infectious disease
AB We thank Ferhat Arslan  for this letter. Biological significance is certainly the most important aspect in biomedical research; however, statistics provide a powerful tool to reveal associations between biological variables. In our study, we aimed to identify predictor variables for mortality in solid organ transplant recipients with carbapenemase-producing Enterobacteriaceae-bloodstream infections (CPE-BSI) regardless of their causal associations and to analyze the predictive capacity of the model. However, in this case, we consider there is a plausible clinical justification for the variables and interaction obtained in our model. Thus, for the interaction term, it could be interpreted that in high-risk patients, the mortality associated with CPE infection is so high that the impact of a previous cytomegalovirus (CMV) infection would not involve higher mortality.
PB Elsevier
YR 2020
FD 2020-04-12
LK http://hdl.handle.net/10668/15257
UL http://hdl.handle.net/10668/15257
LA en
NO Gutiérrez-Gutiérrez B, Pérez-Nadales E, Rodríguez-Baño J, Torre-Cisneros J. Reply to "CMV merits further evolutionary and biological view". Am J Transplant. 2020 May;20(5):1467-1468
DS RISalud
RD Apr 18, 2025