%0 Journal Article
%A Gutierrez-Gutierrez, Belen
%A Perez-Nadales, Elena
%A Rodriguez-Baño, Jesus
%A Torre-Cisneros, Julian
%T Reply to "CMV merits further evolutionary and biological view".
%D 2020
%U http://hdl.handle.net/10668/15257
%X We thank Ferhat Arslan  for this letter. Biological significance is certainly the most important aspect in biomedical research; however, statistics provide a powerful tool to reveal associations between biological variables. In our study, we aimed to identify predictor variables for mortality in solid organ transplant recipients with carbapenemase-producing Enterobacteriaceae-bloodstream infections (CPE-BSI) regardless of their causal associations and to analyze the predictive capacity of the model. However, in this case, we consider there is a plausible clinical justification for the variables and interaction obtained in our model. Thus, for the interaction term, it could be interpreted that in high-risk patients, the mortality associated with CPE infection is so high that the impact of a previous cytomegalovirus (CMV) infection would not involve higher mortality.
%K Antibiotic drug resistance
%K Clinical research/practice
%K Infection and infectious agents-bacterial
%K Infectious disease
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