RT Journal Article T1 The Biological Contributions to Gender Identity and Gender Diversity: Bringing Data to the Table. A1 Polderman, Tinca J C A1 Kreukels, Baudewijntje P C A1 Irwig, Michael S A1 Beach, Lauren A1 Chan, Yee-Ming A1 Derks, Eske M A1 Esteva, Isabel A1 Ehrenfeld, Jesse A1 Heijer, Martin Den A1 Posthuma, Danielle A1 Raynor, Lewis A1 Tishelman, Amy A1 Davis, Lea K A1 International Gender Diversity Genomics Consortium, K1 Gender dysphoria K1 Gender identity K1 Genetics K1 Heritability K1 Transgender K1 Twin studies AB The American Psychological Association defines gender identity as, "A person's deeply-felt, inherent sense of being a boy, a man, or a male; a girl, a woman, or a female; or an alternative gender (e.g., genderqueer, gender nonconforming, gender neutral) that may or may not correspond to a person's sex assigned at birth or to a person's primary or secondary sex characteristics" (American Psychological Association, Am Psychol 70(9):832-864, 2015). Here we review the evidence that gender identity and related socially defined gender constructs are influenced in part by innate factors including genes. Based on the data reviewed, we hypothesize that gender identity is a multifactorial complex trait with a heritable polygenic component. We argue that increasing the awareness of the biological diversity underlying gender identity development is relevant to all domains of social, medical, and neuroscience research and foundational for reducing health disparities and promoting human-rights protections for gender minorities. YR 2018 FD 2018-02-19 LK http://hdl.handle.net/10668/12154 UL http://hdl.handle.net/10668/12154 LA en DS RISalud RD Apr 4, 2025