TY - JOUR AU - Teruel, María AU - Simeon, Carmen P AU - Broen, Jasper AU - Vonk, Madelon C AU - Carreira, Patricia AU - Camps, Maria Teresa AU - García-Portales, Rosa AU - Delgado-Frías, Esmeralda AU - Gallego, Maria AU - Espinosa, Gerard AU - Beretta, Lorenzo AU - Airó, Paolo AU - Lunardi, Claudio AU - Riemekasten, Gabriela AU - Witte, Torsten AU - Krieg, Thomas AU - Kreuter, Alexander AU - Distler, Jörg H W AU - Hunzelmann, Nicolas AU - Koeleman, Bobby P AU - Voskuyl, Alexandre E AU - Schuerwegh, Annemie J AU - González-Gay, Miguel Angel AU - Radstake, Timothy R D J AU - Martin, Javier PY - 2012 DO - 10.1186/ar3890 SN - 1478-6354 UR - http://hdl.handle.net/10668/1410 T2 - Arthritis research & therapy AB - INTRODUCTIONThe aim of the present study was to investigate the possible role of CD40 and CD40 ligand (CD40LG) genes in the susceptibility and phenotype expression of systemic sclerosis (SSc).METHODSIn total, 2,670 SSc patients and 3,245 healthy... LA - en PB - BioMed Central KW - Ligando CD40 KW - antígenos CD40 KW - Predisposición genética a la enfermedad KW - Genotipo KW - Humanos KW - Polimorfismo de Nucleótido Simple KW - Esclerodermia sistémica KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Antigens, Differentiation::Antigens, CD::CD40 Ligand KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide KW - Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Scleroderma, Systemic KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Antigens, Differentiation::Antigens, CD::Antigens, CD40 TI - Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis. TY - research article ER -