TY - JOUR AU - Bayona-Feliu, Aleix AU - Casas-Lamesa, Anna AU - Reina, Oscar AU - Bernués, Jordi AU - Azorín, Fernando PY - 2017 DO - 10.1038/s41467-017-00338-5 UR - http://hdl.handle.net/10668/11518 T2 - Nature communications AB - Linker histone H1 is an important structural component of chromatin that stabilizes the nucleosome and compacts the nucleofilament into higher-order structures. The biology of histone H1 remains, however, poorly understood. Here we show that... LA - en KW - Animals KW - Animals, Genetically Modified KW - Cell Line KW - Chromatin KW - DNA Damage KW - Drosophila Proteins KW - Drosophila melanogaster KW - Gene Expression Profiling KW - Genomic Instability KW - Heterochromatin KW - Histones KW - RNA Interference TI - Linker histone H1 prevents R-loop accumulation and genome instability in heterochromatin. TY - research article VL - 8 ER -