TY  - JOUR
AU  - Gonzalez-Moro, Itziar
AU  - Olazagoitia-Garmendia, Ane
AU  - Colli, Maikel L
AU  - Cobo-Vuilleumier, Nadia
AU  - Postler, Thomas S
AU  - Marselli, Lorella
AU  - Marchetti, Piero
AU  - Ghosh, Sankar
AU  - Gauthier, Benoit R
AU  - Eizirik, Decio L
AU  - Castellanos-Rubio, Ainara
AU  - Santin, Izortze
PY  - 2020
DO  - 10.1073/pnas.1914353117
UR  - http://hdl.handle.net/10668/15369
T2  - Proceedings of the National Academy of Sciences of the United States of America
AB  - The vast majority of type 1 diabetes (T1D) genetic association signals lie in noncoding regions of the human genome. Many have been predicted to affect the expression and secondary structure of long noncoding RNAs (lncRNAs), but the contribution of...
LA  - en
KW  - inflammation
KW  - lncRNA
KW  - pancreatic β-cell
KW  - polymorphism
KW  - type 1 diabetes
KW  - 3' Untranslated Regions
KW  - Cell Survival
KW  - Diabetes Mellitus, Type 1
KW  - Genetic Predisposition to Disease
KW  - HEK293 Cells
KW  - Humans
KW  - Insulin-Secreting Cells
KW  - Jurkat Cells
KW  - Poly I-C
KW  - Polymorphism, Single Nucleotide
KW  - Primary Cell Culture
KW  - RNA Stability
KW  - RNA, Long Noncoding
KW  - RNA, Messenger
KW  - RNA, Viral
KW  - RNA-Binding Proteins
KW  - STAT1 Transcription Factor
KW  - Signal Transduction
KW  - Up-Regulation
TI  - The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA.
TY  - research article
VL  - 117
ER  -