TY - JOUR AU - Fernández-Sáez, Nerea AU - Rubio-Ruiz, Belén AU - Campos, Joaquín M AU - Unciti-Broceta, Asier AU - Carrión, María Dora AU - Camacho, María Encarnación PY - 2019 DO - 10.4155/fmc-2018-0291 UR - http://hdl.handle.net/10668/13423 T2 - Future medicinal chemistry AB - Identification of new antiproliferative compounds. Four series of compounds were synthesized by the Mitsunobu reaction. Their antiproliferative activity was studied against several cancer cells and a noncancerous fibroblast cell line. Their apoptotic... LA - en KW - Mitsunobu KW - antiproliferative activity KW - apoptosis KW - benzoxazine KW - pyridoxazine KW - quinoline KW - Antineoplastic Agents KW - Apoptosis KW - Breast Neoplasms KW - Cell Proliferation KW - Colonic Neoplasms KW - Drug Screening Assays, Antitumor KW - Female KW - HCT116 Cells KW - Halogenation KW - Humans KW - MCF-7 Cells KW - Purines KW - Quinolines KW - Structure-Activity Relationship TI - Purine derivatives with heterocyclic moieties and related analogs as new antitumor agents. TY - research article VL - 11 ER -