RT Journal Article
T1 In Vivo Nutritional Assessment of the Microalga Nannochloropsis gaditana and Evaluation of the Antioxidant and Antiproliferative Capacity of Its Functional Extracts.
A1 Martínez, Rosario
A1 Garcia-Beltran, Alejandro
A1 Kapravelou, Garyfallia
A1 Mesas, Cristina
A1 Cabeza, Laura
A1 Perazzoli, Gloria
A1 Guarnizo, Palmira
A1 Rodriguez-Lopez, Alberto
A1 Andres Vallejo, Roberto
A1 Galisteo, Milagros
A1 Aranda, Pilar
A1 Prados, Jose
A1 Lopez-Jurado, Maria
A1 Melguizo, Consolacion
A1 Porres, Jesus M
K1 Nannochloropsis gaditana
K1 antioxidant capacity
K1 functional extracts
K1 nutrient bioavailability
AB Nannochloropsis gaditana is a microalga with interesting nutritional and functional value due to its high content of protein, polyunsaturated fatty acids, and bioactive compounds. However, the hardness of its cell wall prevents accessibility to these components. This work aimed to study the effect of a treatment to increase the fragility of the cell wall on the bioavailability of its nutrients and functional compounds. The antioxidant and antiproliferative capacity of functional extracts from treated and untreated N. gaditana was assessed, and the profile of bioactive compounds was characterized. Furthermore, to study the effect of treatment on its nutrient availability and functional capacity, an in vivo experiment was carried out using a rat experimental model and a 20% dietary inclusion level of microalgae. Functional extracts from treated N. gaditana exhibited higher antioxidant activity than the untreated control. Furthermore, the treated microalga induced hypoglycemic action, higher nitrogen digestibility, and increased hepatic antioxidant activity. In conclusion, N. gaditana has interesting hepatoprotective, antioxidant, and anti-inflammatory potential, thus proving itself an ideal functional food candidate, especially if the microalga is treated to increase the fragility of its cell wall before consumption.
PB MDPI AG
YR 2022
FD 2022-05-09
LK http://hdl.handle.net/10668/21416
UL http://hdl.handle.net/10668/21416
LA en
NO Martínez R, García-Beltrán A, Kapravelou G, Mesas C, Cabeza L, Perazzoli G, et al. In Vivo Nutritional Assessment of the Microalga Nannochloropsis gaditana and Evaluation of the Antioxidant and Antiproliferative Capacity of Its Functional Extracts. Mar Drugs. 2022 May 11;20(5):318.
DS RISalud
RD Apr 12, 2025