TY - JOUR AU - Lin, Xiaoxiao AU - Chen, Lujia AU - Baglietto-Vargas, David AU - Kamalipour, Parsa AU - Ye, Qiao AU - LaFerla, Frank M AU - Nitz, Douglas A AU - Holmes, Todd C AU - Xu, Xiangmin PY - 2021 DO - 10.1016/j.nbd.2021.105562 UR - http://hdl.handle.net/10668/22402 T2 - Neurobiology of disease AB - Alzheimer's disease (AD) causes progressive age-related defects in memory and cognitive function and has emerged as a major health and socio-economic concern in the US and worldwide. To develop effective therapeutic treatments for AD, we need to... LA - en KW - 3xTg-AD KW - Aging KW - Alzheimer's disease KW - Calcium imaging KW - Freely behaving mice KW - In vivo imaging KW - Miniscope KW - Alzheimer Disease KW - Amyloid beta-Protein Precursor KW - Animals KW - Calcium KW - Disease Models, Animal KW - Hippocampus KW - Mice KW - Mice, Transgenic KW - tau Proteins TI - Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model. TY - research article VL - 162 ER -