RT Journal Article
T1 Plasma phospholipid long-chain n-3 polyunsaturated fatty acids and body weight change.
A1 Jakobsen, Marianne U.
A1 Dethlefsen, Claus
A1 Due, Karen M.
A1 Slimani, Nadia
A1 Chajès, Veronique
A1 May, Anne M.
A1 Sørensen, Thorkild I A.
A1 Halkjær, Jytte
A1 Tjønneland, Anne
A1 Clavel-Chapelon, Francoise
A1 Boutron-Ruault, Marie-Christine
A1 Fagherazzi, Guy
A1 Teucher, Birgit
A1 Kaaks, Rudolf
A1 Boeing, Heiner
A1 Schütze, Madlen
A1 Trichopoulou, Antonia
A1 Zylis, Dimosthenis
A1 Makrygiannis, George
A1 Palli, Domenico
A1 Mattiello, Amalia
A1 Tagliabue, Giovanna
A1 van der A, Daphne L.
A1 Bueno-de-Mesquita, H B
A1 Rodríguez, Laudina
A1 Travier, Noémie
A1 Molina-Montes, Esther
A1 Huerta, José M.
A1 Barricarte, Aurelio
A1 Amiano, Pilar
A1 Manjer, Jonas
A1 Wirfält, Elisabet
A1 Johansson, Ingegerd
A1 Hallmans, Göran
A1 Khaw, Kay-Tee
A1 Wareham, Nicholas J.
A1 Crowe, Francesca
A1 Romieu, Isabelle
A1 Riboli, Elio
A1 Peeters, Petra H M
A1 Overvad, Kim
K1 Body weight
K1 Cohort study
K1 n-3 fatty acids
K1 Omega-3 fatty acids
K1 Weight change
K1 Ácidos grasos omega-3
K1 Femenino
K1 Humanos
K1 Modelos lineales
K1 Masculino
K1 Mediana edad
K1 Obesidad
K1 Fosfolípidos
K1 Estudios prospectivos
K1 Peso corporal
AB OBJECTIVEWe investigated the association between the proportion of long-chain n-3 polyunsaturated fatty acids (PUFA) in plasma phospholipids from blood samples drawn at enrollment and subsequent change in body weight. Sex, age, and BMI were considered as potential effect modifiers.METHODA total of 1,998 women and men participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) were followed for a median of 4.9 years. The associations between the proportion of plasma phospholipid long-chain n-3 PUFA and change in weight were investigated using mixed-effect linear regression.RESULTSThe proportion of long-chain n-3 PUFA was not associated with change in weight. Among all participants, the 1-year weight change was -0.7 g per 1% point higher long-chain n-3 PUFA level (95% confidence interval: -20.7 to 19.3). The results when stratified by sex, age, or BMI groups were not systematically different.CONCLUSIONThe results of this study suggest that the proportion of long-chain n-3 PUFA in plasma phospholipids is not associated with subsequent change in body weight within the range of exposure in the general population.
PB KARGER
SN 1662-4025
YR 2011
FD 2011-08-01
LK http://hdl.handle.net/10668/1999
UL http://hdl.handle.net/10668/1999
LA en
NO Jakobsen MU, Dethlefsen C, Due KM, Slimani N, Chajès V, May AM, et al. Plasma phospholipid long-chain n-3 polyunsaturated fatty acids and body weight change. Obes Facts 2011; 4(4):312-8
NO Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 19, 2025