%0 Journal Article
%A Jakobsen, Marianne U.
%A Dethlefsen, Claus
%A Due, Karen M.
%A Slimani, Nadia
%A Chajès, Veronique
%A May, Anne M.
%A Sørensen, Thorkild I A.
%A Halkjær, Jytte
%A Tjønneland, Anne
%A Clavel-Chapelon, Francoise
%A Boutron-Ruault, Marie-Christine
%A Fagherazzi, Guy
%A Teucher, Birgit
%A Kaaks, Rudolf
%A Boeing, Heiner
%A Schütze, Madlen
%A Trichopoulou, Antonia
%A Zylis, Dimosthenis
%A Makrygiannis, George
%A Palli, Domenico
%A Mattiello, Amalia
%A Tagliabue, Giovanna
%A van der A, Daphne L.
%A Bueno-de-Mesquita, H B
%A Rodríguez, Laudina
%A Travier, Noémie
%A Molina-Montes, Esther
%A Huerta, José M.
%A Barricarte, Aurelio
%A Amiano, Pilar
%A Manjer, Jonas
%A Wirfält, Elisabet
%A Johansson, Ingegerd
%A Hallmans, Göran
%A Khaw, Kay-Tee
%A Wareham, Nicholas J.
%A Crowe, Francesca
%A Romieu, Isabelle
%A Riboli, Elio
%A Peeters, Petra H M
%A Overvad, Kim
%T Plasma phospholipid long-chain n-3 polyunsaturated fatty acids and body weight change.
%D 2011
%@ 1662-4025
%U http://hdl.handle.net/10668/1999
%X OBJECTIVEWe investigated the association between the proportion of long-chain n-3 polyunsaturated fatty acids (PUFA) in plasma phospholipids from blood samples drawn at enrollment and subsequent change in body weight. Sex, age, and BMI were considered as potential effect modifiers.METHODA total of 1,998 women and men participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) were followed for a median of 4.9 years. The associations between the proportion of plasma phospholipid long-chain n-3 PUFA and change in weight were investigated using mixed-effect linear regression.RESULTSThe proportion of long-chain n-3 PUFA was not associated with change in weight. Among all participants, the 1-year weight change was -0.7 g per 1% point higher long-chain n-3 PUFA level (95% confidence interval: -20.7 to 19.3). The results when stratified by sex, age, or BMI groups were not systematically different.CONCLUSIONThe results of this study suggest that the proportion of long-chain n-3 PUFA in plasma phospholipids is not associated with subsequent change in body weight within the range of exposure in the general population.
%K Body weight
%K Cohort study
%K n-3 fatty acids
%K Omega-3 fatty acids
%K Weight change
%K Ácidos grasos omega-3
%K Femenino
%K Humanos
%K Modelos lineales
%K Masculino
%K Mediana edad
%K Obesidad
%K Fosfolípidos
%K Estudios prospectivos
%K Peso corporal
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