RT Journal Article
T1 Unique Features of a Unique Cell: The Wonder World of GnRH Neurons.
A1 Roa, Juan
A1 Tena-Sempere, Manuel
K1 Animals
K1 Dendrimers
K1 Female
AB Reproduction is driven by the interplay of multiple neural and hormonal signals. Sophisticated neuronal circuits have evolved to govern gonadal function and transmit the influence of various internal and environmental cues on reproductive capacity (1, 2). Most of these regulatory factors impinge, directly or indirectly, on a final common pathway formed by neurons in the basal forebrain that produce GnRH (2). The discovery of GnRH in the 1970s opened up a new era in reproductive physiology and medicine, as illustrated not only by the growing clinical use of GnRH analogs but also by recognition of the fundamental role of pulsatile GnRH secretion in the control of puberty and fertility. Deregulation of GnRH pulsatility is involved in different reproductive conditions, such as polycystic ovary syndrome and hypothalamic amenorrhea.
PB Oxford University Press
YR 2018
FD 2018-10-11
LK http://hdl.handle.net/10668/13102
UL http://hdl.handle.net/10668/13102
LA en
NO Roa J, Tena-Sempere M. Unique Features of a Unique Cell: The Wonder World of GnRH Neurons. Endocrinology. 2018 Dec 1;159(12):3895-3896
DS RISalud
RD Apr 7, 2025