TY - JOUR AU - Ruiz-Cantero, M Carmen AU - Gonzalez-Cano, Rafael AU - Tejada, Miguel A AU - Santos-Caballero, Miriam AU - Perazzoli, Gloria AU - Nieto, Francisco R AU - Cobos, Enrique J PY - 2020 DO - 10.1016/j.phrs.2020.105339 UR - http://hdl.handle.net/10668/16733 T2 - Pharmacological research AB - Immune and glial cells play a pivotal role in chronic pain. Therefore, it is possible that the pharmacological modulation of neurotransmission from an exclusively neuronal perspective may not be enough for adequate pain management, and the modulation... LA - en PB - Elsevier Ltd KW - Astrocyte KW - Endogenous opioid analgesia KW - Macrophage KW - Microglia KW - Neuroinflammation KW - Pain KW - Analgesia KW - Analgesics KW - Animals KW - Chronic Pain KW - Humans KW - Inflammation KW - Morpholines KW - Neuralgia KW - Neuroglia KW - Pyrazoles KW - Receptors, sigma KW - Sex Characteristics TI - Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain. TY - research article VL - 163 ER -