RT Journal Article
T1 COVID-19-related echocardiographic patterns of cardiovascular dysfunction in critically ill patients: A systematic review of the current literature.
A1 Messina, Antonio
A1 Sanfilippo, Filippo
A1 Milani, Angelo
A1 Calabrò, Lorenzo
A1 Negri, Katerina
A1 Monge García, Manuel Ignacio
A1 Astuto, Marinella
A1 Vieillard-Baron, Antoine
A1 Cecconi, Maurizio
K1 COVID-19
K1 Critical care
K1 Diastolic function
K1 Echocardiography
K1 Left ventricle
K1 Right ventricle
K1 Systolic function
AB Coronavirus disease 2019 (COVID-19) infection may trigger a multi-systemic disease involving different organs. There has been growing interest regarding the harmful effects of COVID-19 on the cardiovascular system. This systematic review aims to systematically analyze papers reporting echocardiographic findings in hospitalized COVID-19 subjects. We included prospective and retrospective studies reporting echocardiography data in >10 hospitalized adult subjects with COVID-19; from 1st February 2020 to 15th January 2021. The primary electronic search identified 1120 articles. Twenty-nine studies were finally included, enrolling 3944 subjects. Overall the studies included a median of 68.0% (45.5-100.0) of patients admitted to ICU. Ten studies (34.4%) were retrospective, and 20 (68.9%) single-centred. Overall enrolling 1367 subjects, three studies reported normal echocardiographic findings in 49 ± 18% of cases. Seven studies (24.1%) analyzed the association between echocardiographic findings and mortality, mostly related to right ventricular (RV) dysfunction. Data regarding the use of echocardiography on hospitalized, predominantly ICU, COVID-19 patients were retrieved from studies with heterogeneous designs, variable sample sizes, and severity scores. Normal echocardiographic findings were reported in about 50% of subjects, with LVEF usually not affected. Overall, RV dysfunction seems more likely associated with increased mortality. CRD42020218439.
YR 2021
FD 2021-05-25
LK https://hdl.handle.net/10668/25037
UL https://hdl.handle.net/10668/25037
LA en
DS RISalud
RD Apr 6, 2025