TY - JOUR AU - Garcia-Dominguez, Daniel J AU - Hontecillas-Prieto, Lourdes AU - Leon, Eduardo Andres AU - Sanchez-Molina, Sara AU - Rodriguez-Nuñez, Pablo AU - Moron, Francisco J AU - Hajji, Nabil AU - Mackintosh, Carlos AU - de-Alava, Enrique PY - 2020 DO - 10.1371/journal.pone.0234243 UR - http://hdl.handle.net/10668/15686 T2 - PloS one AB - The presence of the chimeric EWSR1-FLI1 oncoprotein is the main and initiating event defining Ewing sarcoma (ES). The dysregulation of epigenomic and proteomic homeostasis induced by the oncoprotein contributes to a wide variety of events involved in... LA - en PB - Public Library of Science KW - Binding Sites KW - DNA KW - HeLa Cells KW - Oncogene Proteins, Fusion KW - Carcinogenesis KW - Ectopic Gene Expression KW - Humans KW - Sarcoma, Ewing TI - An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis. TY - research article VL - 15 ER -