RT Generic T1 Role of fluorine-18 fluorodeoxyglucose PET/CT in head and neck oncology: the point of view of the radiation oncologist A1 Cacicedo, Jon A1 Navarro, Arturo A1 del Hoyo, Olga A1 Gomez-Iturriaga, Alfonso A1 Along, Filippo A1 Medina, Jose A. A1 Elicin, Olgun A1 Skanjeti, Andrea A1 Giammarile, Francesco A1 Bilbao, Pedro A1 Casquero, Francisco A1 de Bari, Berardino A1 Dal Pra, Alan K1 Positron-emission-tomography K1 Squamous-cell carcinoma K1 Metabolic tumor volume K1 Contrast-enhanced ct K1 Standardized uptake value K1 Total lesion glycolysis K1 Unknown primary tumors K1 Lymph-node metastases K1 2nd primary tumors K1 Locally advanced head AB Squamous cell carcinoma is the most common malignant tumour of the head and neck. The initial TNM staging, the evaluation of the tumour response during treatment, and the long-term surveillance are crucial moments in the approach to head and neck squamous cell carcinoma (HNSCC). Thus, at each of these moments, the choice of the best diagnostic tool providing the more precise and larger information is crucial. Positron emission tomography with fluorine-18 fludeoxyglucose integrated with CT (F-18-FDG-PET/CT) rapidly gained clinical acceptance, and it has become an important imaging tool in routine clinical oncology. However, controversial data are currently available, for example, on the role of F-18-FDG-PET/CT imaging during radiotherapy planning, the prognostic value or its real clinical impact on treatment decisions. In this article, the role of F-18-FDG-PET/CT imaging in HNSCC during pre-treatment staging, radiotherapy planning, treatment response assessment, prognosis and follow-up is reviewed focusing on current evidence and controversial issues. A proposal on how to integrate F-18-FDG-PET/CT in daily clinical practice is also described. PB British inst radiology SN 0007-1285 YR 2016 FD 2016-01-01 LK http://hdl.handle.net/10668/19142 UL http://hdl.handle.net/10668/19142 LA en DS RISalud RD Apr 10, 2025