RT Journal Article
T1 Consumption of fruits, vegetables and fruit juices and differentiated thyroid carcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
A1 Zamora-Ros, Raul
A1 Béraud, Virginie
A1 Franceschi, Silvia
A1 Cayssials, Valerie
A1 Tsilidis, Konstantinos K
A1 Boutron-Ruault, Marie-Christine
A1 Weiderpass, Elisabete
A1 Overvad, Kim
A1 Tjønneland, Anne
A1 Eriksen, Anne K
A1 Bonnet, Fabrice
A1 Affret, Aurélie
A1 Katzke, Verena
A1 Kühn, Tilman
A1 Boeing, Heiner
A1 Trichopoulou, Antonia
A1 Valanou, Elisavet
A1 Karakatsani, Anna
A1 Masala, Giovanna
A1 Grioni, Sara
A1 Santucci de Magistris, Maria
A1 Tumino, Rosario
A1 Ricceri, Fulvio
A1 Skeie, Guri
A1 Parr, Christine L
A1 Merino, Susana
A1 Salamanca-Fernández, Elena
A1 Chirlaque, Maria-Dolores
A1 Ardanaz, Eva
A1 Amiano, Pilar
A1 Almquist, Martin
A1 Drake, Isabel
A1 Hennings, Joakim
A1 Sandström, Maria
A1 Bueno-de-Mesquita, H B As
A1 Peeters, Petra H
A1 Khaw, Kay-Thee
A1 Wareham, Nicholas J
A1 Schmidt, Julie A
A1 Perez-Cornago, Aurora
A1 Aune, Dagfinn
A1 Riboli, Elio
A1 Slimani, Nadia
A1 Scalbert, Augustin
A1 Romieu, Isabelle
A1 Agudo, Antonio
A1 Rinaldi, Sabina
K1 EPIC
K1 fruit juices
K1 fruits
K1 intake
K1 thyroid cancer
K1 vegetables
AB Fruit and vegetable (F&V) intake is considered as probably protective against overall cancer risk, but results in previous studies are not consistent for thyroid cancer (TC). The purpose of this study is to examine the association between the consumption of fruits, vegetables, fruit juices and differentiated thyroid cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The EPIC study is a cohort including over half a million participants, recruited between 1991 and 2000. During a mean follow-up of 14 years, 748 incident first primary differentiated TC cases were identified. F&V and fruit juice intakes were assessed through validated country-specific dietary questionnaires. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression models adjusted for potential confounding factors. Comparing the highest versus lowest quartile of intake, differentiated TC risk was not associated with intakes of total F&V (HR: 0.89; 95% CI: 0.68-1.15; p-trend = 0.44), vegetables (HR: 0.89; 95% CI: 0.69-1.14; p-trend = 0.56), or fruit (HR: 1.00; 95% CI: 0.79-1.26; p-trend = 0.64). No significant association was observed with any individual type of vegetable or fruit. However, there was a positive borderline trend with fruit juice intake (HR: 1.23; 95% CI: 0.98-1.53; p-trend = 0.06). This study did not find any significant association between F&V intakes and differentiated TC risk; however a positive trend with fruit juice intake was observed, possibly related to its high sugar content.
YR 2017
FD 2017-07-24
LK http://hdl.handle.net/10668/11386
UL http://hdl.handle.net/10668/11386
LA en
DS RISalud
RD Apr 8, 2025