TY - JOUR AU - Tayara, Khadija AU - Espinosa-Oliva, Ana M AU - Garcia-Dominguez, Irene AU - Ismaiel, Afrah Abdul AU - Boza-Serrano, Antonio AU - Deierborg, Tomas AU - Machado, Alberto AU - Herrera, Antonio J AU - Venero, Jose L AU - de-Pablos, Rocio M PY - 2018 DO - 10.3389/fncel.2018.00440 SN - 1662-5102 UR - http://hdl.handle.net/10668/13284 T2 - Frontiers in cellular neuroscience AB - The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, thus protecting various brain tissues as cortical neurons, for example. However, the effect of metformin on the substantia nigra... LA - en PB - Frontiers Research Foundation KW - AMPK KW - Parkinson’s disease KW - animal model KW - metformin KW - microglia activation KW - neuroinflammation KW - Lipopolysaccharides KW - Microglia KW - Dopaminergic Neurons KW - Adenylate Kinase KW - Arginase KW - Cytokines KW - Mitogens KW - Metformin TI - Divergent Effects of Metformin on an Inflammatory Model of Parkinson's Disease. TY - research article VL - 12 ER -