RT Journal Article T1 Multiple sclerosis and alcohol use disorders: In-hospital mortality, extended hospital stays, and overexpenditures. T2 Esclerosis múltiple y trastornos asociados al consumo de alcohol: mortalidad atribuible, prolongación de estancias y exceso de costes hospitalarios. A1 Gili-Miner, M A1 López-Méndez, J A1 Vilches-Arenas, A A1 Ramírez-Ramírez, G A1 Franco-Fernández, D A1 Sala-Turrens, J A1 Béjar-Prado, L K1 Alcohol use disorders K1 Costes K1 Costs K1 Esclerosis múltiple K1 Estancia hospitalaria K1 Hospital stay K1 Mortalidad K1 Mortality K1 Multiple sclerosis K1 Trastornos asociados al consumo de alcohol AB The objective of this study was to analyse the impact of alcohol use disorders (AUD) in patients with multiple sclerosis (MS) in terms of in-hospital mortality, extended hospital stays, and overexpenditures. We conducted a retrospective observational study in a sample of MS patients obtained from minimal basic data sets from 87 Spanish hospitals recorded between 2008 and 2010. Mortality, length of hospital stays, and overexpenditures attributable to AUD were calculated. We used a multivariate analysis of covariance to control for such variables as age and sex, type of hospital, type of admission, other addictions, and comorbidities. The 10,249 patients admitted for MS and aged 18-74 years included 215 patients with AUD. Patients with both MS and AUD were predominantly male, with more emergency admissions, a higher prevalence of tobacco or substance use disorders, and higher scores on the Charlson comorbidity index. Patients with MS and AUD had a very high in-hospital mortality rate (94.1%) and unusually lengthy stays (2.4 days), and they generated overexpenditures (1,116.9euros per patient). According to the results of this study, AUD in patients with MS results in significant increases in-hospital mortality and the length of the hospital stay and results in overexpenditures. YR 2016 FD 2016-10-22 LK https://hdl.handle.net/10668/27673 UL https://hdl.handle.net/10668/27673 LA en LA es DS RISalud RD Apr 5, 2025