TY - JOUR AU - García-Donas, Jesus AU - Font, Albert AU - Pérez-Valderrama, Begoña AU - Virizuela, José Antonio AU - Climent, Miquel Ángel AU - Hernando-Polo, Susana AU - Arranz, José Ángel AU - Del Mar Llorente, Maria AU - Lainez, Nuria AU - Villa-Guzmán, José Carlos AU - Mellado, Begoña AU - González Del Alba, Aránzazu AU - Castellano, Daniel AU - Gallardo, Enrique AU - Anido, Urbano AU - García Del Muro, Xavier AU - Domènech, Montserrat AU - Puente, Javier AU - Morales-Barrera, Rafael AU - Pérez-Gracia, Jose Luis AU - Bellmunt, Joaquim PY - 2017 DO - 10.1016/S1470-2045(17)30242-5 UR - http://hdl.handle.net/10668/11067 T2 - The Lancet. Oncology AB - Maintenance therapy improves outcomes in various tumour types, but cumulative toxic effects limit the choice of drugs. We investigated whether maintenance therapy with vinflunine would delay disease progression in patients with advanced urothelial... LA - en KW - Adult KW - Aged KW - Aged, 80 and over KW - Antineoplastic Agents KW - Antineoplastic Combined Chemotherapy Protocols KW - Asthenia KW - Carboplatin KW - Carcinoma, Transitional Cell KW - Cisplatin KW - Constipation KW - Deoxycytidine KW - Disease Progression KW - Disease-Free Survival KW - Fatigue KW - Female KW - Follow-Up Studies KW - Humans KW - Intention to Treat Analysis KW - Maintenance Chemotherapy KW - Male KW - Middle Aged KW - Neutropenia KW - Urologic Neoplasms KW - Vinblastine KW - Gemcitabine TI - Maintenance therapy with vinflunine plus best supportive care versus best supportive care alone in patients with advanced urothelial carcinoma with a response after first-line chemotherapy (MAJA; SOGUG 2011/02): a multicentre, randomised, controlled, open-label, phase 2 trial. TY - research article VL - 18 ER -