TY - JOUR AU - Leiter, Lawrence A AU - Cariou, Bertrand AU - Müller-Wieland, Dirk AU - Colhoun, Helen M AU - Del Prato, Stefano AU - Tinahones, Francisco J AU - Ray, Kausik K AU - Bujas-Bobanovic, Maja AU - Domenger, Catherine AU - Mandel, Jonas AU - Samuel, Rita AU - Henry, Robert R PY - 2017 DO - 10.1111/dom.13114 UR - http://hdl.handle.net/10668/11579 T2 - Diabetes, obesity & metabolism AB - To investigate the efficacy and safety of alirocumab in participants with type 2 (T2D) or type 1 diabetes (T1D) treated with insulin who have elevated LDL cholesterol levels despite maximally tolerated statin therapy. Participants at high... LA - en KW - cardiovascular disease KW - clinical trial KW - lipid-lowering therapy KW - type 1 diabetes KW - type 2 diabetes KW - Aged KW - Aged, 80 and over KW - Antibodies, Monoclonal KW - Antibodies, Monoclonal, Humanized KW - Anticholesteremic Agents KW - Cardiovascular Diseases KW - Diabetes Mellitus, Type 1 KW - Diabetes Mellitus, Type 2 KW - Diabetic Angiopathies KW - Diabetic Cardiomyopathies KW - Double-Blind Method KW - Drug Administration Schedule KW - Drug Resistance KW - Female KW - Humans KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - Hypercholesterolemia KW - Hypoglycemic Agents KW - Injections, Subcutaneous KW - Insulin KW - Male KW - Middle Aged KW - Risk TI - Efficacy and safety of alirocumab in insulin-treated individuals with type 1 or type 2 diabetes and high cardiovascular risk: The ODYSSEY DM-INSULIN randomized trial. TY - research article VL - 19 ER -