RT Generic
T1 Clinicopathologic Features of Advanced Squamous NSCLC.
A1 Socinski, Mark A
A1 Obasaju, Coleman
A1 Gandara, David
A1 Hirsch, Fred R
A1 Bonomi, Philip
A1 Bunn, Paul
A1 Kim, Edward S
A1 Langer, Corey J
A1 Natale, Ronald B
A1 Novello, Silvia
A1 Paz-Ares, Luis
A1 Perol, Maurice
A1 Reck, Martin
A1 Ramalingam, Suresh S
A1 Reynolds, Craig H
A1 Spigel, David R
A1 Stinchcombe, Thomas E
A1 Wakelee, Heather
A1 Mayo, Carlos
A1 Thatcher, Nick
K1 Etiology
K1 Histologic Subtype
K1 NSCLC
K1 Squamous cell lung cancer
AB Lung cancer remains the leading cause of cancer-related death worldwide. NSCLC accounts for more than 85% of all lung cancers, and the prognosis for advanced-stage disease is typically poor. In recent years, the importance of histologic subtypes of NSCLC has been recognized, and the distinction between squamous and other NSCLC histologic subtypes is now critical to patient management. Squamous cell lung cancer (sqCLC) represents approximately 25% to 30% of NSCLC. The prognosis for patients with advanced NSCLC is poorer for those with sqCLC than for those with adenocarcinoma. This is partly due to a number of clinical characteristics that distinguish sqCLC from other NSCLC histologic subtypes, such as smoking history, comorbid diseases, age, and molecular profile. Together, these factors make sqCLC an especially challenging disease to manage. Herein, we review some of the key clinicopathologic features of sqCLC. Understanding these features to optimally address many of the unique therapeutic challenges of this disease is likely to be central to ultimately improving outcomes for patients with squamous NSCLC.
PB Elsevier Inc.
YR 2016
FD 2016-06-10
LK http://hdl.handle.net/10668/10170
UL http://hdl.handle.net/10668/10170
LA en
NO Socinski MA, Obasaju C, Gandara D, Hirsch FR, Bonomi P, Bunn P, et al. Clinicopathologic Features of Advanced Squamous NSCLC. J Thorac Oncol. 2016 Sep;11(9):1411-22.
DS RISalud
RD Apr 7, 2025