TY - JOUR AU - Romero-Pico, Amparo AU - Novelle, Marta G AU - Al-Massadi, Omar AU - Beiroa, Daniel AU - Tojo, Marta AU - Heras, Violeta AU - Ruiz-Pino, Francisco AU - Senra, Ana AU - Lopez, Miguel AU - Blouet, Clemence AU - Tena-Sempere, Manuel AU - Nogueiras, Ruben AU - Dieguez, Carlos PY - 2022 DO - 10.3390/ijms23063118 UR - http://hdl.handle.net/10668/21143 T2 - International journal of molecular sciences AB - Weight gain is a hallmark of decreased estradiol (E2) levels because of menopause or following surgical ovariectomy (OVX) at younger ages. Of note, this weight gain tends to be around the abdomen, which is frequently associated with impaired metabolic... LA - en PB - MDPI KW - Energy expenditure KW - Estrogens KW - Kappa-opioid KW - Obesity KW - p70S6K KW - Adipose tissue, brown KW - Animals KW - Body weight KW - Eating KW - Energy metabolism KW - Estrogens KW - Female KW - Humans KW - Mice KW - Obesity KW - Ovariectomy KW - Receptors, opioid, kappa KW - TOR serine-threonine kinases KW - Weight gain TI - Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway. TY - research article VL - 23 ER -