TY  - JOUR
AU  - López-Longarela, Barbara
AU  - Morrison, Emma E
AU  - Tranter, John D
AU  - Chahman-Vos, Lianne
AU  - Léonard, Jean-François
AU  - Gautier, Jean-Charles
AU  - Laurent, Sébastien
AU  - Lartigau, Aude
AU  - Boitier, Eric
AU  - Sautier, Lucile
AU  - Carmona-Saez, Pedro
AU  - Martorell-Marugan, Jordi
AU  - Mellanby, Richard J
AU  - Pernagallo, Salvatore
AU  - Ilyine, Hugh
AU  - Rissin, David M
AU  - Duffy, David C
AU  - Dear, James W
AU  - Díaz-Mochón, Juan J
PY  - 2020
DO  - 10.1021/acs.analchem.9b05449
UR  - http://hdl.handle.net/10668/14958
T2  - Analytical chemistry
AB  - Circulating microRNAs are biomarkers reported to be stable and translational across species. MicroRNA-122 (miR-122) is a hepatocyte-specific microRNA biomarker for drug-induced liver injury (DILI). We developed a single molecule, dynamic chemical...
LA  - en
KW  - Acetaminophen
KW  - Adolescent
KW  - Adult
KW  - Animals
KW  - Biomarkers
KW  - Chemical and Drug Induced Liver Injury
KW  - Dogs
KW  - Hepatocytes
KW  - Humans
KW  - Male
KW  - MicroRNAs
KW  - Rats
KW  - Young Adult
TI  - Direct Detection of miR-122 in Hepatotoxicity Using Dynamic Chemical Labeling Overcomes Stability and isomiR Challenges.
TY  - research article
VL  - 92
ER  -