RT Journal Article T1 Prevalence of asthma-like symptoms with ageing. A1 Jarvis, Debbie A1 Newson, Roger A1 Janson, Christer A1 Corsico, Angelo A1 Heinrich, Joachim A1 Anto, Josep M A1 Abramson, Michael J A1 Kirsten, Anne-Marie A1 Zock, Jan Paul A1 Bono, Roberto A1 Demoly, Pascal A1 Leynaert, Bénédicte A1 Raherison, Chantal A1 Pin, Isabelle A1 Gislason, Thorarinn A1 Jogi, Rain A1 Schlunssen, Vivi A1 Svanes, Cecilie A1 Watkins, John A1 Weyler, Joost A1 Pereira-Vega, Antonio A1 Urrutia, Isabel A1 Gullón, Jose A A1 Forsberg, Bertil A1 Probst-Hensch, Nicole A1 Boezen, H Marike A1 Martinez-Moratalla Rovira, Jesús A1 Accordini, Simone A1 de Marco, Roberto A1 Burney, Peter K1 Asthma Epidemiology AB Change in the prevalence of asthma-like symptoms in populations of ageing adults is likely to be influenced by smoking, asthma treatment and atopy. The European Community Respiratory Health Survey collected information on prevalent asthma-like symptoms from representative samples of adults aged 20-44 years (29 centres in 13 European countries and Australia) at baseline and 10 and 20 years later (n=7844). Net changes in symptom prevalence were determined using generalised estimating equations (accounting for non-response through inverse probability weighting), followed by meta-analysis of centre level estimates. Over 20 years the prevalence of 'wheeze' and 'wheeze in the absence of a cold' decreased (-2.4%, 95% CI -3.5 to -1.3%; -1.5%, 95% CI -2.4 to -0.6%, respectively) but the prevalence of asthma attacks, use of asthma medication and hay fever/nasal allergies increased (0.6%, 95% CI 0.1 to 1.11; 3.6%, 95% CI 3.0 to 4.2; 2.7%, 95% CI 1.7 to 3.7). Changes were similar in the first 10 years compared with the second 10 years, except for hay fever/nasal allergies (increase seen in the first 10 years only). Decreases in these wheeze-related symptoms were largely seen in the group who gave up smoking, and were seen in those who reported hay fever/nasal allergies at baseline. European adults born between 1946 and 1970 have, over the last 20 years, experienced less wheeze, although they were more likely to report asthma attacks, use of asthma medication and hay fever. Decrease in wheeze is largely attributable to smoking cessation, rather than improved treatment of asthma. It may also be influenced by reductions in atopy with ageing. YR 2017 FD 2017-10-03 LK http://hdl.handle.net/10668/11646 UL http://hdl.handle.net/10668/11646 LA en DS RISalud RD Apr 9, 2025