RT Journal Article
T1 Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging: a pooled analysis of individual patient data.
A1 García Castillo, Elena
A1 Alonso Pérez, Tamara
A1 Ancochea, Julio
A1 Pastor Sanz, Maria Teresa
A1 Almagro, Pere
A1 Martínez-Camblor, Pablo
A1 Miravitlles, Marc
A1 Rodríguez-Carballeira, Mónica
A1 Navarro, Annie
A1 Lamprecht, Bernd
A1 Ramírez-García Luna, Ana S
A1 Kaiser, Bernhard
A1 Alfageme, Inmaculada
A1 Casanova, Ciro
A1 Esteban, Cristóbal
A1 Soler-Cataluña, Juan J
A1 de-Torres, Juan P
A1 Celli, Bartolomé R
A1 Marín, Jose M
A1 Ter Riet, Gerben
A1 Sobradillo, Patricia
A1 Lange, Peter
A1 Garcia-Aymerich, Judith
A1 Anto, Josep M
A1 Turner, Alice M
A1 Han, MeiLan K
A1 Langhammer, Arnulf
A1 Vikjord, Sigrid Anna Aalberg
A1 Sternberg, Alice
A1 Leivseth, Linda
A1 Bakke, Per
A1 Johannessen, Ane
A1 Oga, Toru
A1 Cosío, Borja G
A1 Echazarreta, Andrés
A1 Roche, Nicolás
A1 Burgel, Pierre-Régis
A1 Sin, Don D
A1 Puhan, Milo A
A1 López-Campos, Jose Luis
A1 Carrasco, Laura
A1 Soriano, Joan B
AB In 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system for patients with COPD, creating 16 subgroups (1A-4D). As part of the COPD Cohorts Collaborative International Assessment (3CIA) initiative, we aim to compare the mortality prediction of the 2015 and 2019 COPD GOLD staging systems. We studied 17 139 COPD patients from the 3CIA study, selecting those with complete data. Patients were classified by the 2015 and 2019 GOLD ABCD systems, and we compared the predictive ability for 5-year mortality of both classifications. In total, 17 139 patients with COPD were enrolled in 22 cohorts from 11 countries between 2003 and 2017; 8823 of them had complete data and were analysed. Mean±sd age was 63.9±9.8 years and 62.9% were male. GOLD 2019 classified the patients in milder degrees of COPD. For both classifications, group D had higher mortality. 5-year mortality did not differ between groups B and C in GOLD 2015; in GOLD 2019, mortality was greater for group B than C. Patients classified as group A and B had better sensitivity and positive predictive value with the GOLD 2019 classification than GOLD 2015. GOLD 2015 had better sensitivity for group C and D than GOLD 2019. The area under the curve values for 5-year mortality were only 0.67 (95% CI 0.66-0.68) for GOLD 2015 and 0.65 (95% CI 0.63-0.66) for GOLD 2019. The new GOLD 2019 classification does not predict mortality better than the previous GOLD 2015 system.
SN 2312-0541
YR 2020
FD 2020-11-02
LK https://hdl.handle.net/10668/27872
UL https://hdl.handle.net/10668/27872
LA en
DS RISalud
RD Apr 17, 2025