TY - JOUR AU - Pintado, Cristina AU - Macías, Sandra AU - Domínguez-Martín, Helena AU - Castaño, Angélica AU - Ruano, Diego PY - 2017 DO - 10.1038/s41598-017-08722-3 UR - http://hdl.handle.net/10668/11501 T2 - Scientific reports AB - Proteostasis alteration and neuroinflammation are typical features of normal aging. We have previously shown that neuroinflammation alters cellular proteostasis through immunoproteasome induction, leading to a transient decrease of proteasome... LA - en KW - Activating Transcription Factor 6 KW - Animals KW - Autophagy KW - Cell Line KW - Down-Regulation KW - Endoplasmic Reticulum Stress KW - Endoplasmic Reticulum-Associated Degradation KW - Endoribonucleases KW - Glycogen Synthase Kinase 3 beta KW - Inflammation KW - Male KW - Mice KW - Proteostasis KW - Rats KW - Rats, Wistar KW - Signal Transduction KW - TOR Serine-Threonine Kinases KW - Unfolded Protein Response KW - X-Box Binding Protein 1 TI - Neuroinflammation alters cellular proteostasis by producing endoplasmic reticulum stress, autophagy activation and disrupting ERAD activation. TY - research article VL - 7 ER -