TY - JOUR AU - Vazquez-Carballo, Cristina AU - Herencia, Carmen AU - Guerrero-Hue, Melania AU - Garcia-Caballero, Cristina AU - Rayego-Mateos, Sandra AU - Morgado-Pascual, Jose Luis AU - Opazo-Rios, Lucas AU - Gonzalez-Guerrero, Cristian AU - Vallejo-Mudarra, Mercedes AU - Cortegano, Isabel AU - Gaspar, Maria Luisa AU - de Andres, Belen AU - Egido, Jesus AU - Moreno, Juan Antonio PY - 2022 DO - 10.1002/path.5995 UR - http://hdl.handle.net/10668/22428 T2 - The Journal of pathology AB - Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the circulation, promoting injury in vulnerable organs, mainly kidney, liver, and spleen. Heme... LA - en PB - John Wiley & Sons KW - TLR4 KW - Acute kidney injury KW - Heme KW - Hemoglobin KW - Inflammation KW - Intravascular hemolysis KW - Oxidative stress KW - Animals KW - Disease models, animal KW - Heme KW - Hemolysis KW - Inflammation KW - Mice KW - Mice, knockout KW - NF-kappa B KW - Phenylhydrazines KW - Sulfonamides KW - Toll-like receptor 4 TI - Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury. TY - research article VL - 258 ER -