RT Journal Article
T1 Physical Fitness Attenuates the Impact of Higher Body Mass and Adiposity on Inflammation in Women With Systemic Lupus Erythematosus
A1 Sola-Rodriguez, Sergio
A1 Vargas-Hitos, Jose Antonio
A1 Gavilan-Carrera, Blanca
A1 Rosales-Castillo, Antonio
A1 Rios-Fernandez, Raquel
A1 Sabio, Jose Mario
A1 Soriano-Maldonado, Alberto
K1 obesity
K1 systemic low-grade inflammation
K1 cardiorespiratory fitness
K1 range of motion
K1 flexibility
K1 autoimmune diseases
K1 body mass index
K1 body fat percentage (BF%)
K1 C-reactive protein
K1 Cardiorespiratory fitness
K1 Disease-activity
K1 All-cause
K1 Obesity
K1 Association
K1 Validation
K1 Predictor
K1 Mortality
K1 Capacity
AB Aims Higher body mass and adiposity represent independent contributors to the systemic low-grade inflammatory state often observed in patients with systemic lupus erythematosus (SLE). This study assessed the role of physical fitness in the association of body mass and adiposity with inflammation in women with SLE.Methods A total of 77 women with SLE were included in this cross-sectional study. We obtained body mass index, waist-to-height ratio, and body fat percentage as indicators of body mass and adiposity. Inflammation was assessed through Serum levels of C-reactive protein, interleukin 6, and leptin. Cardiorespiratory fitness was assessed with the 6-minute walk test, range of motion with the back-scratch test, and muscular strength with handgrip dynamometry.Results Cardiorespiratory fitness attenuated the association of both body mass index and body fat percentage with interleukin 6 (all, P
PB Frontiers media sa
SN 1664-3224
YR 2021
FD 2021-10-14
LK https://hdl.handle.net/10668/26139
UL https://hdl.handle.net/10668/26139
LA en
DS RISalud
RD Apr 7, 2025