RT Journal Article
T1 Moderate-Vigorous Physical Activity across Body Mass Index in Females: Moderating Effect of Endocannabinoids and Temperament.
A1 Fernández-Aranda, Fernando
A1 Sauchelli, Sarah
A1 Pastor, Antoni
A1 González, Marcela L
A1 Torre, Rafael de la
A1 Granero, Roser
A1 Jiménez-Murcia, Susana
A1 Baños, Rosa
A1 Botella, Cristina
A1 Fernández-Real, José M
A1 Fernández-García, José C
A1 Frühbeck, Gema
A1 Gómez-Ambrosi, Javier
A1 Rodríguez, Roser
A1 Tinahones, Francisco J
A1 Arcelus, Jon
A1 Fagundo, Ana B
A1 Agüera, Zaida
A1 Miró, Jordi
A1 Casanueva, Felipe F
K1 Esfuerzo físico
K1 Endocannabinoides
K1 Ácidos araquidónicos
K1 Índice de masa corporal
K1 Temperamento
K1 Mujer
K1 Obesidad
AB BACKGROUNDEndocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females. The aims of this cross-sectional study were to 1) examine differences among distinct BMI groups on daytime physical activity and time spent in moderate-vigorous physical activity (MVPA), temperament traits and plasma endocannabinoid concentrations; and 2) explore the association and interaction between MVPA, temperament, endocannabinoids and BMI.METHODSPhysical activity was measured with the wrist-worn accelerometer Actiwatch AW7, in a sample of 189 female participants (43 morbid obese, 30 obese, and 116 healthy-weight controls). The Temperament and Character Inventory-Revised questionnaire was used to assess personality traits. BMI was calculated by bioelectrical impedance analysis via the TANITA digital scale. Blood analyses were conducted to measure levels of endocannabinoids and endocannabinoid-related compounds. Path-analysis was performed to examine the association between predictive variables and MVPA.RESULTSObese groups showed lower MVPA and dysfunctional temperament traits compared to healthy-weight controls. Plasma concentrations of 2-arachidonoylglyceryl (2-AG) were greater in obese groups. Path-analysis identified a direct effect between greater MVPA and low BMI (b = -0.13, p = .039) and high MVPA levels were associated with elevated anandamide (AEA) levels (b = 0.16, p = .049) and N-oleylethanolamide (OEA) levels (b = 0.22, p = .004), as well as high Novelty seeking (b = 0.18, p<.001) and low Harm avoidance (b = -0.16, p<.001).CONCLUSIONSObese individuals showed a distinct temperament profile and circulating endocannabinoids compared to controls. Temperament and endocannabinoids may act as moderators of the low MVPA in obesity.
PB Public Library of Science
YR 2014
FD 2014-08-07
LK http://hdl.handle.net/10668/1851
UL http://hdl.handle.net/10668/1851
LA en
NO Fernández-Aranda F, Sauchelli S, Pastor A, González ML, Torre R de la, Granero R, et al. Moderate-Vigorous Physical Activity across Body Mass Index in Females: Moderating Effect of Endocannabinoids and Temperament. PLoS ONE. 2014; 9(8):e104534
NO Journal Article;
DS RISalud
RD Apr 11, 2025