RT Journal Article T1 Endocrine Disruptors in Food: Impact on Gut Microbiota and Metabolic Diseases A1 Gálvez-Ontiveros, Yolanda A1 Páez, Sara A1 Monteagudo, Celia A1 Rivas, Ana K1 Endocrine disrupters K1 Food K1 Gut microbiota K1 Metabolic diseases K1 Alimentos K1 Microbioma gastrointestinal K1 Enfermedades metabólicas AB Endocrine disruptors (EDCs) have been associated with the increased incidence of metabolic disorders. In this work, we conducted a systematic review of the literature in order to identify the current knowledge of the interactions between EDCs in food, the gut microbiota, and metabolic disorders in order to shed light on this complex triad. Exposure to EDCs induces a series of changes including microbial dysbiosis and the induction of xenobiotic pathways and associated genes, enzymes, and metabolites involved in EDC metabolism. The products and by-products released following the microbial metabolism of EDCs can be taken up by the host; therefore, changes in the composition of the microbiota and in the production of microbial metabolites could have a major impact on host metabolism and the development of diseases. The remediation of EDC-induced changes in the gut microbiota might represent an alternative course for the treatment and prevention of metabolic diseases. PB MDPI YR 2020 FD 2020-04-21 LK http://hdl.handle.net/10668/3570 UL http://hdl.handle.net/10668/3570 LA en NO Gálvez-Ontiveros Y, Páez S, Monteagudo C, Rivas A. Endocrine Disruptors in Food: Impact on Gut Microbiota and Metabolic Diseases. Nutrients. 2020 Apr 21;12(4):1158 DS RISalud RD Apr 11, 2025