RT Journal Article T1 The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome A1 Marcos-Delgado, Alba A1 Fernández-Villa, Tania A1 Martínez-González, Miguel Ángel A1 Salas-Salvadó, Jordi A1 Corella, Dolores A1 Castañer, Olga A1 Martínez, J. Alfredo A1 Alonso-Gómez, Ángel M. A1 Wärnberg, Julia A1 Vioque, Jesús A1 Romaguera, Dora A1 López-Miranda, José A1 Estruch, Ramon A1 Tinahones, Francisco J. A1 Lapetra, José A1 Serra-Majem, J. LLuís A1 García-Molina, Laura A1 Tur, Josep A. A1 de Paz, José Antonio A1 Pintó, Xavier A1 Delgado-Rodríguez, Miguel A1 Matía-Martín, Pilar A1 Vidal, Josep A1 Vázquez, Clotilde A1 Daimiel, Lidia A1 Ros, Emilio A1 Babio, Nancy A1 Gimenez-Alba, Ignacio M. A1 Toledo, Estefanía A1 Zomeño, María Dolores A1 Zulet, M. A. A1 Vaquero-Luna, Jessica A1 Pérez-López, Jessica A1 Pastor-Morel, Ana A1 Galmes-Panades, Aina M. A1 García-Rios, Antonio A1 Casas, Rosa A1 Bernal-López, María Rosa A1 Santos-Lozano, José Manuel A1 Becerra-Tomás, Nerea A1 Ortega-Azorin, Carolina A1 Vázquez-Ruiz, Zenaida A1 Pérez-Vega, Karla Alejandra A1 Abete, Itziar A1 Sorto-Sánchez, Carolina A1 Palau-Galindo, Antoni A1 Galilea-Zabalza, Iñigo A1 Muñoz-Martínez, Júlia A1 Martín, Vicente K1 Health-related quality of life K1 Physical activity K1 Obesity K1 Body mass index K1 Metabolic syndrome K1 Calidad de vida K1 Ejercicio físico K1 Obesidad K1 Índice de masa corporal K1 Síndrome metabólico AB The main objective of this study was to examine the relationship between the level of physical activity (PA) and the degree of obesity with health-related quality of life (HRQoL) in individuals with metabolic syndrome (MetS) who participated in the Predimed-Plus study. A total of 6875 subjects between 55 and 75 years of age with MetS were selected and randomized in 23 Spanish centers. Subjects were classified according to categories of body mass index (BMI). PA was measured with the validated Registre Gironí del Cor (REGICOR) questionnaire and subjects were classified according to their PA level (light, moderate, vigorous) and the HRQoL was measured with the validated short-form 36 (SF-36) questionnaire. By using the ANOVA model, we found a positive and statistically significant association between the level of PA and the HRQoL (aggregated physical and mental dimensions p < 0.001), but a negative association with higher BMI in aggregated physical dimensions p < 0.001. Furthermore, women obtained lower scores compared with men, more five points in all fields of SF-36. Therefore, it is essential to promote PA and body weight control from primary care consultations to improve HRQoL, paying special attention to the differences that sex incurs. PB MDPI SN 1661-7827 YR 2020 FD 2020-05-25 LK http://hdl.handle.net/10668/4368 UL http://hdl.handle.net/10668/4368 LA en NO Marcos-Delgado A, Fernández-Villa T, Martínez-González MÁ, Salas-Salvadó J, Corella D, Castañer O, et al. The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome. Int J Environ Res Public Health. 2020 May 25;17(10):3728 NO Los autores de este artículo forman parte el grupo de investigación PREDIMED-Plus. DS RISalud RD Apr 9, 2025