TY - JOUR AU - Ascierto, Paolo A AU - Dréno, Brigitte AU - Larkin, James AU - Ribas, Antoni AU - Liszkay, Gabriella AU - Maio, Michele AU - Mandalà, Mario AU - Demidov, Lev AU - Stroyakovskiy, Daniil AU - Thomas, Luc AU - de la Cruz-Merino, Luis AU - Atkinson, Victoria AU - Dutriaux, Caroline AU - Garbe, Claus AU - Hsu, Jessie AU - Jones, Surai AU - Li, Haocheng AU - McKenna, Edward AU - Voulgari, Athina AU - McArthur, Grant A PY - 2021 DO - 10.1158/1078-0432.CCR-21-0809 UR - https://hdl.handle.net/10668/27587 T2 - Clinical cancer research : an official journal of the American Association for Cancer Research AB - The randomized phase III coBRIM study (NCT01689519) demonstrated improved progression-free survival (PFS) and overall survival (OS) with addition of cobimetinib to vemurafenib compared with vemurafenib in patients with previously untreated BRAFV600... LA - en KW - Antineoplastic Combined Chemotherapy Protocols KW - Azetidines KW - Follow-Up Studies KW - Humans KW - Melanoma KW - Mutation KW - Piperidines KW - Proto-Oncogene Proteins B-raf KW - Skin Neoplasms KW - Vemurafenib TI - 5-Year Outcomes with Cobimetinib plus Vemurafenib in BRAFV600 Mutation-Positive Advanced Melanoma: Extended Follow-up of the coBRIM Study. TY - research article VL - 27 ER -