TY - JOUR AU - Quintela-Fandino, Miguel AU - Lluch, Ana AU - Manso, Luis AU - Calvo, Isabel AU - Cortes, Javier AU - García-Saenz, José Angel AU - Gil-Gil, Miguel AU - Martinez-Jánez, Noelia AU - Gonzalez-Martin, Antonio AU - Adrover, Encarna AU - de Andres, Raquel AU - Viñas, Gemma AU - Llombart-Cussac, Antonio AU - Alba, Emilio AU - Guerra, Juan AU - Bermejo, Begoña AU - Zamora, Esther AU - Moreno-Anton, Fernando AU - Pernas Simon, Sonia AU - Carrato, Alfredo AU - Lopez-Alonso, Antonio AU - Escudero, María José AU - Campo, Ruth AU - Carrasco, Eva AU - Palacios, José AU - Mulero, Francisca AU - Colomer, Ramon PY - 2016 DO - 10.1158/1078-0432.CCR-16-0738 UR - http://hdl.handle.net/10668/10410 T2 - Clinical cancer research : an official journal of the American Association for Cancer Research AB - Purpose: We previously detected promising efficacy of neoadjuvant nintedanib (a multityrosine kinase inhibitor, TKI) in early HER2-negative breast cancer. In a preclinical study, we monitored stromal hypoxia with 18F-fluoromisonidazole-positron... LA - en KW - Adult KW - Aged KW - Aged, 80 and over KW - Breast Neoplasms KW - Female KW - Humans KW - Indoles KW - Middle Aged KW - Misonidazole KW - Neoadjuvant Therapy KW - Neoplasm Staging KW - Paclitaxel KW - Positron Emission Tomography Computed Tomography KW - Protein Kinase Inhibitors KW - Receptor, ErbB-2 KW - Tumor Hypoxia TI - 18F-fluoromisonidazole PET and Activity of Neoadjuvant Nintedanib in Early HER2-Negative Breast Cancer: A Window-of-Opportunity Randomized Trial. TY - research article VL - 23 ER -