RT Journal Article
T1 Dietary Patterns and Prostate Cancer: CAPLIFE Study.
A1 Lozano-Lorca, Macarena
A1 Rodriguez-Gonzalez, Margarita
A1 Salcedo-Bellido, Inmaculada
A1 Vazquez-Alonso, Fernando
A1 Arrabal, Miguel
A1 Martin-Castaño, Benita
A1 Sanchez-Perez, Maria-Jose
A1 Jimenez-Moleon, Jose-Juan
A1 Olmedo-Requena, Rocio
K1 CAPLIFE study
K1 case-control study
K1 dietary patterns
K1 principal component analysis
K1 prostate cancer
AB The etiology of prostate cancer (PCa) remains uncertain, and the role of diet is unclear. We aimed to evaluate the role of diet, through dietary patterns, on PCa, considering tumor aggressiveness and extension. The CAPLIFE study is a population-based case-control study including a total of 428 incident PCa cases and 393 controls aged 40-80 years. Dietary information was collected through a validated food frequency questionnaire. Three dietary patterns were identified through principal component analysis: "Mediterranean," "Western," and "Unhealthy," which were categorized into tertiles according to the control group cutoff points. Tumor aggressiveness and extension was determined. Logistic regression models were used to assess the association between dietary patterns and PCa. High adherence to an unhealthy dietary pattern was associated with higher odds of PCa, ORT3vsT1 = 1.52 (95% CI 1.02-2.27), especially for cases with ISUP 1-2 and localized PCa tumors. This association was not observed with a Western or Mediterranean pattern. In conclusion, adherence to an unhealthy diet appears to be associated with higher odds of PCa, especially for cases with ISUP 1-2 and localized PCa tumors.
PB MDPI AG
SN 2072-6694
YR 2022
FD 2022-07-17
LK http://hdl.handle.net/10668/20907
UL http://hdl.handle.net/10668/20907
LA en
NO Lozano-Lorca M, Rodríguez-González M, Salcedo-Bellido I, Vázquez-Alonso F, Arrabal M, Martín-Castaño B, et al. Dietary Patterns and Prostate Cancer: CAPLIFE Study. Cancers (Basel). 2022 Jul 17;14(14):3475.
DS RISalud
RD Apr 16, 2025