TY - JOUR AU - Avendaño, María S AU - García-Redondo, Ana B AU - Zalba, Guillermo AU - González-Amor, María AU - Aguado, Andrea AU - Martínez-Revelles, Sonia AU - Beltrán, Luis M AU - Camacho, Mercedes AU - Cachofeiro, Victoria AU - Alonso, María J AU - Salaices, Mercedes AU - Briones, Ana M PY - 2018 DO - 10.1161/HYPERTENSIONAHA.118.10833 UR - http://hdl.handle.net/10668/12577 T2 - Hypertension (Dallas, Tex. : 1979) AB - mPGES-1 (microsomal prostaglandin E synthase-1), the downstream enzyme responsible for PGE2 (prostaglandin E2) synthesis in inflammatory conditions and oxidative stress are increased in vessels from hypertensive animals. We evaluated the role of... LA - en KW - angiotensin II KW - hypertension KW - oxidative stress KW - prostaglandins KW - vascular remodeling KW - Animals KW - Carotid Arteries KW - Disease Models, Animal KW - Gene Expression Regulation KW - Humans KW - Hypertension KW - Leukocytes, Mononuclear KW - Mice KW - Mice, Knockout KW - Muscle, Smooth, Vascular KW - Oxidative Stress KW - Prostaglandin-E Synthases KW - RNA KW - Vascular Stiffness TI - mPGES-1 (Microsomal Prostaglandin E Synthase-1) Mediates Vascular Dysfunction in Hypertension Through Oxidative Stress. TY - research article VL - 72 ER -