RT Journal Article T1 The current status of COVID-19 vaccines. A scoping review. A1 Rueda-Fernandez, Manuel A1 Melguizo-Rodriguez, Lucia A1 Costela-Ruiz, Victor J A1 Gonzalez-Acedo, Anabel A1 Ramos-Torrecillas, Javier A1 Illescas-Montes, Rebeca K1 Humans K1 NVX-CoV2373 adjuvated lipid nanoparticle K1 ChAdOx1 nCoV-19 K1 SARS-CoV-2 AB Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new disease that has led to a worldwide pandemic, resulting in millions of deaths and a high economic burden. Here, we analyze the current status of preventive vaccines authorized by the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA). Published clinical trials have shown the effectiveness of mRNA (BNT162b2 and Spikevax), adenovirus vector-based (Ad26.COV2.S and ChAdOx1 nCoV-19), and recombinant protein S (NVX-CoV2373) vaccines to be between 52.9% and 100%. The most-frequent adverse effects include local pain, fatigue, headache, or chills. Serious events are associated with Ad26.COV2.S and ChAdOx1 nCoV-19 vaccines. PB Elsevier Ltd. * Trends Journals YR 2022 FD 2022-08-19 LK http://hdl.handle.net/10668/22156 UL http://hdl.handle.net/10668/22156 LA en NO Rueda-Fernández M, Melguizo-Rodríguez L, Costela-Ruiz VJ, González-Acedo A, Ramos-Torrecillas J, Illescas-Montes R. The current status of COVID-19 vaccines. A scoping review. Drug Discov Today. 2022 Nov;27(11):103336. DS RISalud RD Apr 12, 2025