RT Journal Article T1 Coinfection with HIV and hepatitis C virus in 229 children and young adults living in Europe A1 Thorne, Claire A1 Turkova, Anna A1 Indolfi, Giuseppe A1 Venturini, Elisabetta A1 Giaquinto, Carlo A1 Goetghebuer, Tessa A1 Hainaut, Marc A1 Van der Kelen, Evelyne A1 Koenigs, Christoph A1 Mantzsch, Kathleen A1 Baumann, Ulrich A1 de Martino, Maurizio A1 Galli, Luisa A1 Giacomet, Vania A1 Nicolini, Laura Ambra A1 Del Puente, Filippo A1 Gabiano, Clara A1 Guarino, Alfredo A1 Martinazzi, Silvia A1 Miniaci, Angela A1 Dobsz, Sabina A1 Marczynska, Magdalena A1 Ene, Luminita A1 Duiculescu, Dan A1 Miloenko, Milana A1 Dodonov, Konstantin A1 Latysheva, Inga A1 Voronin, Evgeny A1 Rojo, Pablo A1 Tomas Ramos, Jose A1 Navarro, Marisa A1 Jimenez de Ory, Santiago A1 Sainz, Talia A1 Mellado, Maria J. A1 Garcia, Miluca A1 Perez, Carlos A1 Moreno, David A1 Nunez, Esmeralda A1 Gracia, Mercedes A1 Terol, Pedro A1 Neth, Olaf A1 Falcon, Lola A1 Otero, Carmen A1 Rincon, Elena A1 Lopez, Carmen A1 Luis Santos, Juan A1 Couceiro, Jose A1 Noguera-Julian, Antoni A1 Fortuny, Claudia A1 Soler-Palacin, Pere A1 Espiau, Maria A1 Mur, Antonio A1 Coll, Maria T. A1 Valmanya, Maria T. A1 Mayol, Luis A1 Mendez, Maria J. A1 Rodrigo, Carlos A1 Escribano, Joaquin A1 Rius, Neus A1 Rovira, Nuria A1 Calavia, Olga A1 Garcia, Lourdes A1 Pineda, Valenti A1 Soriano-Arandes, Antoni A1 Rudin, Christoph A1 Duppenthaler, Andrea A1 Judd, Ali A1 Malyuta, Ruslan A1 Volokha, Alla A1 Raus, Irina A1 Kaleeva, T. A1 Baryshnikova, Y. A1 Soloha, Svetlana A1 Bashkatova, N. A1 Glutshenko, O. A1 Ruban, Z. A1 Primak, Natalia A1 Kiseleva, Galina A1 European Paediat HIV HCV, K1 coinfection K1 hepatitis C K1 HIV K1 paediatric K1 vertical infection K1 Human-immunodeficiency-virus K1 Simple noninvasive index K1 Antiretroviral therapy K1 Pegylated interferon K1 Fibrosis progression K1 St-petersburg K1 Liver K1 Impact K1 Transmission K1 Adolescents AB Objective:To characterize children, adolescents and young adults infected with HIV/hepatitis C virus (HCV) vertically or before age of 18 years and living in Europe regarding mode of acquisition, HCV genotype, clinical status and treatment.Design:Retrospective, cross-sectional study using pooled data from 11 European paediatric HIV cohorts.Methods:Patients aged more than 18 months and less than 25 years, with HIV/HCV acquired vertically or in childhood, were included. Anonymized individual patient data were collected using a standard protocol and modified HIV Cohorts Data Exchange Protocol.Results:Of 229 patients included, 142 (62%) had vertically acquired infection. Median age at last follow-up was 16.2 years. Most children had HCV genotype 1 (101/184, 55%) or 3 (57/184, 31%). One-fifth (46/214) had a previous AIDS diagnosis (data missing on prior AIDS diagnoses for 15). At their last clinic visit, 70% (145/208) had no/mild immunosuppression (Centers for Disease Control and Prevention stage 1), and 131 of 179 on antiretroviral therapy had undetectable HIV RNA (assay thresholds varied from PB Lippincott williams & wilkins SN 0269-9370 YR 2017 FD 2017-01-02 LK https://hdl.handle.net/10668/26391 UL https://hdl.handle.net/10668/26391 LA en DS RISalud RD Apr 12, 2025