%0 Journal Article
%A Thorne, Claire
%A Turkova, Anna
%A Indolfi, Giuseppe
%A Venturini, Elisabetta
%A Giaquinto, Carlo
%A Goetghebuer, Tessa
%A Hainaut, Marc
%A Van der Kelen, Evelyne
%A Koenigs, Christoph
%A Mantzsch, Kathleen
%A Baumann, Ulrich
%A de Martino, Maurizio
%A Galli, Luisa
%A Giacomet, Vania
%A Nicolini, Laura Ambra
%A Del Puente, Filippo
%A Gabiano, Clara
%A Guarino, Alfredo
%A Martinazzi, Silvia
%A Miniaci, Angela
%A Dobsz, Sabina
%A Marczynska, Magdalena
%A Ene, Luminita
%A Duiculescu, Dan
%A Miloenko, Milana
%A Dodonov, Konstantin
%A Latysheva, Inga
%A Voronin, Evgeny
%A Rojo, Pablo
%A Tomas Ramos, Jose
%A Navarro, Marisa
%A Jimenez de Ory, Santiago
%A Sainz, Talia
%A Mellado, Maria J.
%A Garcia, Miluca
%A Perez, Carlos
%A Moreno, David
%A Nunez, Esmeralda
%A Gracia, Mercedes
%A Terol, Pedro
%A Neth, Olaf
%A Falcon, Lola
%A Otero, Carmen
%A Rincon, Elena
%A Lopez, Carmen
%A Luis Santos, Juan
%A Couceiro, Jose
%A Noguera-Julian, Antoni
%A Fortuny, Claudia
%A Soler-Palacin, Pere
%A Espiau, Maria
%A Mur, Antonio
%A Coll, Maria T.
%A Valmanya, Maria T.
%A Mayol, Luis
%A Mendez, Maria J.
%A Rodrigo, Carlos
%A Escribano, Joaquin
%A Rius, Neus
%A Rovira, Nuria
%A Calavia, Olga
%A Garcia, Lourdes
%A Pineda, Valenti
%A Soriano-Arandes, Antoni
%A Rudin, Christoph
%A Duppenthaler, Andrea
%A Judd, Ali
%A Malyuta, Ruslan
%A Volokha, Alla
%A Raus, Irina
%A Kaleeva, T.
%A Baryshnikova, Y.
%A Soloha, Svetlana
%A Bashkatova, N.
%A Glutshenko, O.
%A Ruban, Z.
%A Primak, Natalia
%A Kiseleva, Galina
%A European Paediat HIV HCV
%T Coinfection with HIV and hepatitis C virus in 229 children and young adults living in Europe
%D 2017
%@ 0269-9370
%U https://hdl.handle.net/10668/26391
%X Objective:To characterize children, adolescents and young adults infected with HIV/hepatitis C virus (HCV) vertically or before age of 18 years and living in Europe regarding mode of acquisition, HCV genotype, clinical status and treatment.Design:Retrospective, cross-sectional study using pooled data from 11 European paediatric HIV cohorts.Methods:Patients aged more than 18 months and less than 25 years, with HIV/HCV acquired vertically or in childhood, were included. Anonymized individual patient data were collected using a standard protocol and modified HIV Cohorts Data Exchange Protocol.Results:Of 229 patients included, 142 (62%) had vertically acquired infection. Median age at last follow-up was 16.2 years. Most children had HCV genotype 1 (101/184, 55%) or 3 (57/184, 31%). One-fifth (46/214) had a previous AIDS diagnosis (data missing on prior AIDS diagnoses for 15). At their last clinic visit, 70% (145/208) had no/mild immunosuppression (Centers for Disease Control and Prevention stage 1), and 131 of 179 on antiretroviral therapy had undetectable HIV RNA (assay thresholds varied from
%K coinfection
%K hepatitis C
%K HIV
%K paediatric
%K vertical infection
%K Human-immunodeficiency-virus
%K Simple noninvasive index
%K Antiretroviral therapy
%K Pegylated interferon
%K Fibrosis progression
%K St-petersburg
%K Liver
%K Impact
%K Transmission
%K Adolescents
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