TY  - JOUR
AU  - Carrasco-Hernández, Laura
AU  - Quintana-Gallego, Esther
AU  - Calero, Carmen
AU  - Reinoso-Arija, Rocío
AU  - Ruiz-Duque, Borja
AU  - López-Campos, José Luis
PY  - 2021
DO  - 10.3390/biomedicines9101437
UR  - http://hdl.handle.net/10668/4400
T2  - Biomedicines
AB  - In recent years, numerous pathways were explored in the pathogenesis of COPD in the quest for new potential therapeutic targets for more personalised medical care. In this context, the study of the cystic fibrosis transmembrane conductance regulator...
LA  - en
PB  - MDPI
KW  - Cystic fibrosis transmembrane conductance regulator
KW  - COPD
KW  - CFTR modulators
KW  - Ivacaftor
KW  - Icenticaftor
KW  - Mucociliary clearance
KW  - Mucus
KW  - Inflammation
KW  - Phosphodiesterase inhibitors
KW  - Regulador de conductancia de transmembrana de fibrosis quística
KW  - Enfermedad pulmonar obstructiva crónica
KW  - Depuración mucociliar
KW  - Moco
KW  - Inflamación
KW  - Inhibidores de fosfodiesterasa
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Membrane Transport Proteins::Ion Channels::Chloride Channels::Cystic Fibrosis Transmembrane Conductance Regulator
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Respiratory System::Mucociliary Clearance
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Protein S
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Physicochemical Phenomena::Viscosity
KW  - Medical Subject Headings::Diseases::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic Obstructive
KW  - Medical Subject Headings::Anatomy::Fluids and Secretions::Bodily Secretions::Mucus
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Phosphodiesterase Inhibitors
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Fluid Therapy
KW  - Medical Subject Headings::Organisms::Bacteria
KW  - Medical Subject Headings::Organisms::Viruses
TI  - Dysfunction in the Cystic Fibrosis Transmembrane Regulator in Chronic Obstructive Pulmonary Disease as a Potential Target for Personalised Medicine
TY  - review article
ER  -