TY  - JOUR
AU  - Jiménez-López, Julia
AU  - Bravo-Caparrós, Inmaculada
AU  - Cabeza, Laura
AU  - Nieto, Francisco R.
AU  - Ortiz, Raúl
AU  - Perazzoli, Gloria
AU  - Fernández-Segura, Eduardo
AU  - Cañizares, Francisco J.
AU  - Baeyens, José M.
AU  - Melguizo, Consolación
AU  - Prados, José
PY  - 2020
DO  - 10.1016/j.biopha.2020.111059
SN  - 0753-3322
UR  - http://hdl.handle.net/10668/4432
T2  - Biomedicine & Pharmacotherapy
AB  - Paclitaxel (PTX), a drug widely used in lung cancer, has serious limitations including the development of peripheral neurotoxicity, which may lead to treatment discontinuation and therapy failure. The transport of PTX in large cationic liposomes could...
LA  - en
PB  - Elsevier Masson SAS
KW  - Lung cancer
KW  - Paclitaxel
KW  - Pegylated liposomes
KW  - Peripheral neurotoxicity
KW  - Dorsal root ganglia
KW  - Liposomes
KW  - Multicellular tumor spheroids
KW  - Polyethylene glycol
KW  - Cancer stem cells
KW  - Neoplasias pulmonares
KW  - Ganglios espinales
KW  - Liposomas
KW  - Esferoides celulares
KW  - Polietilenglicoles
KW  - Células madre neoplásicas
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents::Antineoplastic Agents, Phytogenic
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Technology, Pharmaceutical::Drug Compounding
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Lipids
KW  - Medical Subject Headings::Chemicals and Drugs::Biomedical and Dental Materials::Membranes, Artificial::Liposomes
KW  - Medical Subject Headings::Diseases::Respiratory Tract Diseases::Lung Diseases::Lung Neoplasms
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Laboratory::Animals, Inbred Strains::Mice, Inbred Strains::Mice, Inbred C57BL
KW  - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neoplastic Stem Cells
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Alicyclic::Cycloparaffins::Cyclodecanes::Taxoids::Paclitaxel
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Physicochemical Phenomena::Particle Size
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Neuromuscular Diseases::Peripheral Nervous System Diseases
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Alcohols::Glycols::Ethylene Glycols::Polyethylene Glycols
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Tumor Burden
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Spheroids, Cellular
KW  - Medical Subject Headings::Anatomy::Nervous System::Ganglia::Ganglia, Sensory::Ganglia, Spinal
KW  - Medical Subject Headings::Phenomena and Processes::Biological Phenomena::Ecological and Environmental Phenomena::Environment::Atmosphere::Weather::Temperature::Hot Temperature
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis
TI  - Paclitaxel antitumor effect improvement in lung cancer and prevention of the painful neuropathy using large pegylated cationic liposomes
TY  - research article
ER  -