RT Journal Article
T1 Association of 25-hydroxyvitamin D with metabolic syndrome in patients with psoriasis: a case-control study.
A1 Orgaz-Molina, Jacinto
A1 Magro-Checa, César
A1 Arrabal-Polo, Miguel A
A1 Raya-Álvarez, Enrique
A1 Naranjo, Ramón
A1 Buendía-Eisman, Agustín
A1 Arias-Santiago, Salvador
K1 Psoriasis
K1 Vitamin D
K1 Metabolic syndrome
K1 Cardiovascular risk
K1 Psoriasis
K1 Vitamina D
K1 Enfermedades metabólicas
K1 Enfermedades cardiovasculares
AB Vitamin D deficiency is associated with higher cardiovascular risk and metabolic syndrome (MeS) criteria. The main objective of this study was to analyse the association of 25-hydroxyvitamin D (25-OHD) serum levels with MeS (National Cholesterol Education Program-Adult Treatment Panel-III criteria) in 46 Spanish patients with psoriasis, but without arthritis and systemic treatment, and 46 control subjects, matched by sex and age. The patients with psoriasis showed significantly lower level of 25-OHD than controls (30.5 vs. 38.3 ng/ml; p = 0.0001). Patients with MeS had significantly lower serum levels of 25-OHD than those without MeS (24.1 ± 7.5 vs. 32.8 ± 8.9, p = 0.007), and a negative correlation was found between 25-OHD and waist circumference, diastolic blood pressure, fasting glucose, and triglyceridaemia. In the control group no significant correlation between 25-OHD and MeS was found. Al-though the sample was small, our results suggest a potential protective role for 25-OHD in the metabolic profile of patients with psoriasis without arthritis.
PB Society for Publication of Acta Dermato-Venereologica
SN 0001-5555
YR 2014
FD 2014-03
LK http://hdl.handle.net/10668/1861
UL http://hdl.handle.net/10668/1861
LA en
NO Orgaz-Molina J, Magro-Checa C, Arrabal-Polo MA, Raya-Álvarez E, Naranjo R, Buendía-Eisman A, et al. Association of 25-hydroxyvitamin D with metabolic syndrome in patients with psoriasis: a case-control study. Acta Derm. Venereol.. 2014; 94(2):142-5
NO Journal Article;
DS RISalud
RD Apr 6, 2025