RT Journal Article
T1 Association between common cardiovascular risk factors and clinical phenotype in patients with hypertrophic cardiomyopathy from the European Society of Cardiology (ESC) EurObservational Research Programme (EORP) Cardiomyopathy/Myocarditis registry.
A1 Lopes, Luis R
A1 Losi, Maria-Angela
A1 Sheikh, Nabeel
A1 Laroche, Cécile
A1 Charron, Philippe
A1 Gimeno, Juan
A1 Kaski, Juan P
A1 Maggioni, Aldo P
A1 Tavazzi, Luigi
A1 Arbustini, Eloisa
A1 Brito, Dulce
A1 Celutkiene, Jelena
A1 Hagege, Albert
A1 Linhart, Ales
A1 Mogensen, Jens
A1 Garcia-Pinilla, José Manuel
A1 Ripoll-Vera, Tomas
A1 Seggewiss, Hubert
A1 Villacorta, Eduardo
A1 Caforio, Alida
A1 Elliott, Perry M
A1 Cardiomyopathy Registry Investigators Group, 
K1 Cardiovascular risk factors
K1 Diabetes
K1 Genotype
K1 Hypertension
K1 Hypertrophic cardiomyopathy
K1 Obesity
AB The interaction between common cardiovascular risk factors (CVRF) and hypertrophic cardiomyopathy (HCM) is poorly studied. We sought to explore the relation between CVRF and the clinical characteristics of patients with HCM enrolled in the EURObservational Research Programme (EORP) Cardiomyopathy registry. 1739 patients with HCM were studied. The relation between hypertension (HT), diabetes (DM), body mass index (BMI), and clinical traits was analysed. Analyses were stratified according to the presence or absence of a pathogenic variant in a sarcomere gene. The prevalence of HT, DM, and obesity (Ob) was 37, 10, and 21%, respectively. HT, DM, and Ob were associated with older age (P Common CVRF are associated with a more severe HCM phenotype, suggesting a proactive management of CVRF should be promoted. An interaction between genotype and CVRF was observed for some traits.
YR 2022
FD 2022
LK http://hdl.handle.net/10668/19763
UL http://hdl.handle.net/10668/19763
LA en
DS RISalud
RD Apr 16, 2025